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Fasting Mimicking Diets Have Been Shown to Help…

> Decrease Weight and Body Fat*
> Stem Cell Generation
> Maintain Glucose at Healthy Levels
> Maintain CRP at Healthy Levels
> Maintain Triglycerides at Healthy Levels
> Maintain Blood Pressure at Healthy Levels*
> Maintain Lean Body Mass
> Impact in IGF-1 (Aging Marker)*
> Maintain Insulin Resistance at Healthy Levels
> Maintain Cholesterol at Healthy Levels
> Decrease Visceral Fat*

Clinical Results

In the latest clinical trial conducted at the Longevity Institute at USC and the Diabetes and Obesity Research Institute*, 3 cycles of ProLon®, 5 days per month over a 3 month period produced important metabolic effects. Some of these results are statistically significant 005-2at 1 week after the last cycle).

*Science Translational Medicine – February 2017
Wei et al, Sci. Transl. Med.

Clinical Study Results

IGF-1, marker associated with increased mortality and DNA damage in human cells, was reduced by 14%.

C-reactive protein (CRP) levels decreased from 1.5 mg/L to 1.0 mg/L after participants had resumed their normal diet for 5-8 days after cycle 3.

A transient, major, and significant elevation of stem cell/regenerative markers was also observed.

Participants lost an average of 5 lbs.

Blood pressure (BP) was significantly reduced from 117.4 to 113.6 mm Hg (systolic).

Total cholesterol was reduced nearly 10 mg/dl with significant reductions of LDL from 104.9 to 99.2 mg/dl.

The weight loss came mostly from abdominal fat shown as reduction in abdominal fat mass.

> 1-inch loss in waist circumference.

Lean body mass was preserved.

And 75.7 to 72.8 mm Hg (diastolic).

Elevated Risk Cohort Results

In obese participants (BMl>30), body weight decreased 9 lbs.

Weight remained significantly lower after subjects returned to their normal diet for an average of 3 months. In overweight participants (BMl>25), abdominal fat was reduced by >7%.

With preserved relative lean body mass and decreased waist circumference by approximately >3 cm.

In participants with high cholesterol (>199 mg/dl), total cholesterol was reduced by 20 mg/dl and LD-cholesterol reduced by 15 mg/dl.

lGF-1, was reduced by 20% in participants with high lGF-1 levels.

In participants at an average risk for developing cardiovascular disease (C-reactive protein between 1-3 mg/L), CRP was lowered >1 mg/L closer to the lowest risk range.


In participants with high triglycerides (>100 mg/dl), triglyceride levels were reduced by >25 mg/dl.

For participants with high blood pressure (>120/80) systolic and diastolic BPs were reduced by >6 mmHg.

Blood pressure remained significantly reduced after subjects returned to their normal diet for an average of 3 months. In high fasting glucose participants (>99mg/dl), fasting glucose was reduced by (>10mg/dl) and remained reduced after subjects returned to their normal diet for an average of 3 months; in low glucose participants (<99 mg/dl), fasting glucose remained unchanged.

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